Notes on radiotherapy & chemotherapy – Praesidium Life

Notes on radiotherapy & chemotherapy

The following are notes from Dr Ruggiero on Praesidium as it relates to subjects undergoing radiotherapy or chemotherapy:

First of all, it is important to realize that ionizing radiations of radiotherapy and chemotherapeutic agents exert a very similar type of damage at the cellular and molecular level. This consists in the formation of Reactive Oxygen Species (ROS) that, among other effects, cause lipid peroxidation and DNA breaks.

When I was at the University of Firenze, Italy, we approached these topics when we studied the role of glutathione, a key player in the cellular defenses against ROS, in cancer cells that were resistant to the killing effects of ionizing radiations.

It may be worth noticing that I have been working on these topics for almost 30 years, as demonstrated by the following scientific article, retrievable from PubMed, dating back to the early Nineties, see

Later, we studied multi-drug resistance, a fairly common occurrence in cancer chemotherapy, as it relates to susceptibility to ionizing radiations of the type used in radiotherapy. The scientific article - where also I am the senior author as in the previous one - reporting the in vitro results we obtained in 1996 can be retrieved from PubMed at

In other experiments, we studied the relationship between radio- and chemotherapy when we evaluated the effects of a known chemotherapeutic agent, gemcitabine, on radiation sensitivity. Also this article can be retrieved from PubMed at

The similarity in the type of damage induced by ionizing radiations and chemotherapy can be found in a number of other articles retrievable from PubMed such as, for example, the following article

Therefore, it can be hypothesized that an agent, such as Praesidium, that contains elements with demonstrated ability to counteract the harmful effects of ionizing radiations at the same time optimizing the therapeutic efficacy of radiotherapy, may exert the same effects in the case of chemotherapy.

Before describing the effects of each component of Praesidium, it is important to realize that Praesidium is much more than the sum of its components, as thoroughly described in the following article

In short, each component of Praesidium synergizes with the others so that the overall efficacy of Praesidium is postulated to be much greater than the sum of the efficacies of its individual components.

Each component of Praesidium has, at the same time, radioprotection and anti-cancer activities as demonstrated by a number of peer-reviewed publications. Please find below the links to some examples.

Arthrospira platensis (Spirulina) and radioprotection.


Arthrospira platensis anti-cancer properties


Probiotics and radioprotection


Probiotics anti-cancer properties


Equisetum and radioprotection


Equisetum anti-cancer properties


Therefore, there is ample scientific background to hypothesize that taking Praesidium before, during, and after radio- or chemotherapy may help mitigate the side effects of these therapies, at the same time optimizing their curative efficacy.

Please notice that when any supplement, including Praesidium, is taken in conjunction with a standard-of-care therapeutic approach such as, for example, radio- or chemotherapy for cancer, it is mandatory to communicate with the caring health practitioner (an oncologist in this case) so that the caring doctor is aware of the nature and the composition of the supplement and may advise accordingly.

Although the efficacy of Praesidium as far as non-ionizing EMFs are concerned can be evaluated by measuring Heart Rate Variability (HRV), in case of cancer radio- or chemotherapy, the best evaluation can be achieved by monitoring the known symptoms associated with the side effects of these therapies as well as the therapeutic efficacy. In an ideal scenario, it may be hypothesized that Praesidium could decrease the side effects at the same time optimizing the therapeutic efficacy.